2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. 5-HT Receptor
  5. 5-HT3 Receptor Isoform
  6. 5-HT3 Receptor Inhibitor

5-HT3 Receptor Inhibitor

5-HT3 Receptor Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-15414
    Vortioxetine
    		Inhibitor 99.81%
    Vortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
  • HY-15414A
    Vortioxetine hydrobromide
    		Inhibitor 99.91%
    Vortioxetine hydrobromide is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
  • HY-B0352S
    Mirtazapine-d3
    		Inhibitor 98.55%
    Mirtazapine-d3 is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1].
  • HY-U00413
    5-HT3-In-1
    		Inhibitor
    5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows 5-HT3 inhibition activity.